Wikipedia의 정의에 의하면,
Genome annotation is the process of attaching biological information to sequences. It consists of two main steps:
- identifying elements on the genome, a process called gene prediction, and
- attaching biological information to these elements.
Structural annotation consists of the identification of genomic elements.
- ORFs and their localisation
- gene structure
- coding regions
- location of regulatory motifs
Functional annotation consists of attaching biological information to genomic elements.
- biochemical function
- biological function
- involved regulation and interactions
- expression
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